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Fair Value, Inputs, Level 3 [Member] Level 3 APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation expense Fair Value, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Net (decrease) increase in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Payables and Accruals [Abstract] Number of marketable securities. Number of Marketable Securities Number of marketable securities General and Administrative Expense [Member] General and Administrative Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Number of Shares, Forfeited Options, Cancelled/Forfeited Summary of Dilutive Securities Excluded from Computation of Diluted Net Loss Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] City Area Code City Area Code Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities: Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Document Information [Line Items] Long-term restricted cash, end of period Restricted Cash and Cash Equivalents, Noncurrent, Total Restricted Cash and Cash Equivalents, Noncurrent Restricted cash and deposits, net of current portion Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less—accumulated depreciation General and Administrative Expense, Total General and Administrative Expense General and administrative Weighted Average Number of Shares Outstanding, Basic, Total Weighted Average Number of Shares Outstanding, Basic Weighted average common stock outstanding - basic Research and Development Arrangement, Contract to Perform for Others, Type [Domain] Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Aggregate research collaboration fees Aggregate Research Collaboration Fees Aggregate research collaboration fees Schedule of Nonvested Restricted Stock Units Activity Schedule of Nonvested Restricted Stock Units Activity [Table Text Block] Statement [Table] Statement [Table] Share-Based Payment Arrangement, Option, Activity [Table Text Block] Summary of Combined Stock Option Activity under 2018 Plan and 2021 Plan Schedule of Fair Value of Stock Options, Valuation Assumptions Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Document Fiscal Period Focus Document Fiscal Period Focus Lessee, Operating Lease, Liability, to be Paid Total lease payments Estimated payments due 2026 Lessee, Operating Lease, Liability, to be Paid, Year Two Statement [Line Items] Statement [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Total potential dilutive shares Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value Ending Balance Beginning Balance Installment one. Installment One [Member] Installment One Collaboration Research and Development Agreement. Collaboration Research And Development Agreement [Member] Collaboration Research and Development Agreement Lease, Cost Total lease costs Letters of Credit Outstanding, Amount Letters of credit Common Stock Warrants Common Stock Warrants [Member] Common stock warrants. Asset Class [Domain] Asset Class Royalties on net sales Royalties On Net Sales Royalties on net sales Common Stock [Member] Common Stock Prepaid research and development expenses. Prepaid Research And Development Expenses Prepaid research and development expenses Cash and cash equivalents, end of period Cash and Cash Equivalents, at Carrying Value, Ending Balance Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Total Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Summary of Stock-Based Compensation Expense Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Other Assets, Current Other Risk Free Rate Measurement Input, Risk Free Interest Rate [Member] Aggregate Intrinsic Value, Exercisable at March 31, 2024 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Series D convertible preferred stock.. Series D Convertible Preferred Stock [Member] Series D Convertible Preferred Stock Proceeds from Sale of Debt Securities, Available-for-Sale Proceeds from sale of marketable securities Antidilutive Securities, Name [Domain] Antidilutive Securities, Name Table Text Block [Abstract] Entity Bankruptcy Proceedings, Reporting Current Entity Bankruptcy Proceedings, Reporting Current Warrants expiration period Warrants Expiration Period Warrants expiration period 2014 Exclusive Agreement Exclusive license and supply agreement. Exclusive License And Supply Agreement [Member] One time perpetual license agreement fee One Time Perpetual License Agreement fee One time perpetual license agreement fee. Cover [Abstract] Document Fiscal Year Focus Document Fiscal Year Focus License issue fee. License Issue Fee License issue fee Non-refundable, Non- creditable fee Non-refundable, non-creditable fee. Non Refundable Non Creditable Fee Non-refundable, Non- creditable fee Common stock issued under ATM settled in future period Common Stock Issued under ATM Settled in Future Period Common stock issued under ATM settled in future period. Sale of Stock [Domain] Sale of Stock Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Granted, Weighted-Average Grant Date Fair Value Security Exchange Name Security Exchange Name Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Total other comprehensive loss Total other comprehensive income (loss) New Accounting Pronouncements, Policy [Policy Text Block] Recently Adopted Accounting Pronouncements Preferred stock, shares issued Preferred Stock, Shares Issued Preferred stock, shares authorized Preferred Stock, Shares Authorized Operating Costs and Expenses Total operating expenses IT Equipment Technology Equipment [Member] Property, Plant and Equipment, Gross, Ending Balance Property, Plant and Equipment, Gross, Beginning Balance Property, Plant and Equipment, Gross, Total Property, Plant and Equipment, Gross Property and equipment, gross Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Right-of-use assets obtained in exchange for operating lease liabilities Purchase agreement, installment amount paid Payment Of Long Term Purchase Commitment Amount Payment of long term purchase commitment amount. Series A convertible preferred stock. Series A Convertible Preferred Stock [Member] Series A Convertible Preferred Stock Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Cancelled/Forfeited Legal Entity [Axis] Legal Entity Financial Instrument [Axis] Weighted Average Number of Shares Outstanding, Diluted [Abstract] Denominator: Expected term (years) Warrants and Rights Outstanding, Term Accrued Employee Benefits, Current Accrued compensation Class of Warrant or Right [Table] Class Of Warrant Or Right [Table] Stock Issued During Period, Value, Stock Options Exercised Stock option exercises Entity Emerging Growth Company Entity Emerging Growth Company Total intrinsic value of options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Amendment Flag Amendment Flag Annual Development Fee Annual development fee. Annual Development Fee Annual development fee Purchase agreement, number of payment installments Purchase Agreement Number Of Installments Purchase agreement number of installments. Initial license fee for first licensed product Initial License Fee Related To First Licensed Product Initial license fee related to first licensed product. Unrealized Losses Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Operating lease termination date. Operating Lease Termination Date Operating lease termination date Required amendment payment due period Required Amendment Payment Due Period Required amendment payment due period. Leases [Abstract] Financing lease costs. Financing Lease Costs Financing lease costs: Securities Act File Number Entity File Number Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table] Entity Addresses, Address Type [Axis] Sales milestone payments. Sales Milestone Payments Sales milestone payments 2024 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Finance Lease, Weighted Average Discount Rate, Percent Weighted-average discount rate--finance leases Cash, cash equivalents and restricted cash at end of period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance Share-Based Payment Arrangement [Abstract] Warrants measurement input Warrants and Rights Outstanding, Measurement Input Accounts Payable, Current, Total Accounts Payable, Current Accounts payable Unvested, Weighted -Average Grant Date Fair Value Unvested, Weighted -Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Costs and Expenses, Total Costs and Expenses Expenses Adjustments to Additional Paid in Capital, Other Other Expected term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Entity Small Business Entity Small Business Entity Shell Company Entity Shell Company Class of Warrant or Right, Exercise Price of Warrants or Rights Exercise price of warrants Class of Warrant or Right [Domain] Class of Warrant or Right Payment for use of cell line document package Payment For Use Of Cell Line Document Package payment for use of the cell line document package . S-3 Registration Statement issuance costs Registration Statement Issuance Costs Registration statement issuance costs. Earnings Per Share [Text Block] Net Loss Per Share Commercial Paper Commercial Paper [Member] Entity Address, Address Line One Entity Address, Address Line One Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Common stock warrants disclosure. Common Stock Warrants Disclosure [Text Block] Common Stock Warrants Antidilutive Securities [Axis] Antidilutive Securities Royalty Bearing Patent License Agreement Royalty Bearing Patent License Agreement [Member] Royalty-bearing patent license agreement. Measurement Input, Price Volatility [Member] Volatility Proceeds from issuance of common stock under ATM facility, net of issuance costs Proceeds From Issuance Of Common Stock Under At The Market Facility, Net of Issuance Costs Proceeds from issuance of common stock under at the market facility, net of issuance costs. Subsequent Event Type [Domain] Subsequent Event Type Incurred of expenses related to expansion. Incurred Of Expenses Related To Expansion Incurred of expenses related to expansion Income Statement Location [Axis] Income Statement Location Variable Lease, Cost Variable lease costs Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend rate Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items] Prepaid Insurance Prepaid insurance Purchase agreement, commitments payable in each installment Long-Term Purchase Commitment, Amount Fair Value, Inputs, Level 2 [Member] Level 2 Additional area of rented space. Additional Area Of Rented Space Additional square feet of laboratory space Biologic materials license agreement. Biologic Materials License Agreement [Member] Biologic Materials License Agreement Title of 12(b) Security Title of 12(b) Security Lease Contractual Term [Axis] Lease Contractual Term Dr. John Schiller. Dr John Schiller [Member] Dr. John Schiller Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Marketable Securities, Gain (Loss), Excluding Other-than-temporary Impairment Loss, Total Marketable Security, Gain (Loss) Accretion on marketable securities Accretion on marketable securities License issue royalty fee. License Issue Royalty Fee License issue royalty fee Convertible Preferred Stock Convertible Preferred Stock on an if Converted Basis Convertible preferred stock on if converted basis. Convertible Preferred Stock On If Converted Basis [Member] Long-Lived Tangible Asset [Domain] Long-Lived Tangible Asset Non-exclusive license agreement. Non Exclusive License Agreement [Member] 2014 Non- Exclusive Agreement Other Operating Activities, Cash Flow Statement Other Defined Contribution Plan, Employer Discretionary Contribution Amount Matching contributions from employer Initial license fee. Initial License Fee Initial license fee Weighted Average Remaining Contractual Term (years), Exercisable at March 31, 2024 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding Common stock, shares outstanding Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Share-Based Payment Arrangement [Text Block] Stock-Based Compensation Forfeited, Weighted -Average Grant Date Fair Value Series E convertible preferred stock. Series E Convertible Preferred Stock [Member] Series E Convertible Preferred Stock Common stock outstanding percentage. Common Stock Outstanding Percentage Common stock outstanding percentage Income Statement Location [Domain] Income Statement Location Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Granted Short-term restricted cash, end of period Restricted Cash and Cash Equivalents, Current, Total Restricted Cash and Cash Equivalents, Current Restricted cash and deposits Summary of Changes in Fair Value of Common Stock Warrants Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Document Type Document Type Number of warrants converted into equity instruments Number of common stock upon conversion of convertible preferred stock Stock Issued During Period, Shares, Conversion of Convertible Securities Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Investing Activities Document Quarterly Report Document Quarterly Report Marketable securities Marketable Securities Marketable Securities Forfeited Forfeited Net cash provided by (used in) financing activities Net Cash Provided by (Used in) Financing Activities Entity Filer Category Entity Filer Category Increase (Decrease) in Other Noncurrent Assets Other long-term assets Other long-term assets Increase (Decrease) in Accrued Liabilities, Total Increase (Decrease) in Accrued Liabilities Accrued expenses and other liabilities Restricted Stock Units that Vest into Common Stock Restricted Stock Units that Vest into Common Stock [Member] Restricted stock units that vest into common stock. Purchase of marketable securities Payments to Acquire Marketable Securities Payments to Acquire Marketable Securities, Total Asset Class [Axis] Asset Class Total other income Nonoperating Income (Expense) Lease commencement date Lease Commencement Date Lease commencement date. Capital Expenditures Incurred but Not yet Paid Purchases of property and equipment in accounts payable and accrued expenses and other liabilities Total Liabilities Liabilities Property, Plant and Equipment [Table] Schedule Of Property Plant And Equipment [Table] Impairments of asset Asset Impairment Charges Asset Impairment Charges, Total Total Stockholders' Equity Equity, Attributable to Parent Ending Balance Beginning Balance first payment due. First Payment Due First payment due Net loss Net loss Net losses Other income (expense): Nonoperating Income (Expense) [Abstract] Business Description and Basis of Presentation [Text Block] Description of Business Cumulative increase in shares of common stock. Cumulative Increase In Shares Of Common Stock Cumulative increase in shares of common stock Corporate Bonds Corporate Debt Securities [Member] Statement of Financial Position [Abstract] Area of space leased Area of Real Estate Property Weighted Average Number of Shares Outstanding, Diluted, Total Weighted Average Number of Shares Outstanding, Diluted Weighted average common stock outstanding - diluted Purchase price per share Shares Issued, Price Per Share Share price Effective tax rate Effective Income Tax Rate Reconciliation, Percent, Total Effective Income Tax Rate Reconciliation, Percent Clearside Clearside Biomedical Inc Agreement [Member] Clearside Biomedical Inc agreement. Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Operating Lease, Weighted Average Remaining Lease Term Weighted-average remaining lease term—operating leases (years) Income Tax Disclosure [Text Block] Income Taxes Landlord termination expense Landlord Termination Expense Landlord termination expense. Net proceeds from issuance of follow on offering. Net Proceeds From Issuance Of Follow On Offering Net proceeds from follow-on offering Expense related to agreement including sublicense Cost And Expense Related To Agreement Including Sublicense Cost and expense related to agreement including sublicense. Weighted Average Exercise Price, Ending balance Weighted Average Exercise Price, Beginning balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Summary of Basic and Diluted Net Loss Per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Number of warrants issued Number of Warrants Issued Number of warrants issued. Leasehold Improvements [Member] Leasehold Improvements Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Fair Value Disclosures [Abstract] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV Development and regulatory milestone payments. Development And Regulatory Milestone Payments Development and regulatory milestone payments Measurement Frequency [Domain] Measurement Frequency Payments to Acquire Property, Plant, and Equipment, Total Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Vested/Released Number of awards vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Issuance of common stock, Shares Stock Issued During Period, Shares, New Issues Shares issued and sold Cash and cash equivalents Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Class of Warrant or Right [Axis] Class of Warrant or Right Lessee, operating lease, reimbursement expense. Reimbursed expenses Lessee, Operating Lease, Reimbursement Expense Income Tax Disclosure [Abstract] Summary of Marketable Securities Marketable Securities [Table Text Block] Accrued Expenses and Other Current Liabilities Accrued Expenses And Other Current Liabilities [Text Block] Accrued expenses and other current liabilities.