| 1 | Names of Reporting Persons
Frazier Life Sciences Public Fund, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
5,807,260.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
5,807,260.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
5,807,260.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
5.6 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLSP, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
5,807,260.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
5,807,260.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
5,807,260.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
5.6 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLSP, L.L.C. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
5,807,260.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
5,807,260.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
5,807,260.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
5.6 % |
| 12 | Type of Reporting Person (See Instructions)
OO |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
Frazier Life Sciences X, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
128,520.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
128,520.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
128,520.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.1 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLS X, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
128,520.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
128,520.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
128,520.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.1 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLS X, L.L.C. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
128,520.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
128,520.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
128,520.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.1 % |
| 12 | Type of Reporting Person (See Instructions)
OO |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
Frazier Life Sciences XI, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
358,810.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
358,810.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
358,810.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.3 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLS XI, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
358,810.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
358,810.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
358,810.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.3 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLS XI, L.L.C. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
358,810.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
358,810.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
358,810.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.3 % |
| 12 | Type of Reporting Person (See Instructions)
OO |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
Frazier Life Sciences XII, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
805,410.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
805,410.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
805,410.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.8 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLS XII, L.P. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
805,410.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
805,410.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
805,410.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.8 % |
| 12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
FHMLS XII, L.L.C. |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
DELAWARE
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
805,410.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
805,410.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
805,410.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.8 % |
| 12 | Type of Reporting Person (See Instructions)
OO |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held by the Reporting Person and do not include any warrants held by the Reporting Person. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
James N. Topper |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
UNITED STATES
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
128,520.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
128,520.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
128,520.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.1 % |
| 12 | Type of Reporting Person (See Instructions)
IN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held directly by Frazier Life Sciences X, L.P. and do not include any warrants held directly by Frazier Life Sciences X, L.P. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.
| 1 | Names of Reporting Persons
Patrick J. Heron |
| 2 | Check the appropriate box if a member of a Group (see instructions)
 (a)
 (b)
|
| 3 | Sec Use Only |
| 4 | Citizenship or Place of Organization
UNITED STATES
|
| Number of Shares Beneficially Owned by Each Reporting Person With: | | 5 | Sole Voting Power
0.00 | | 6 | Shared Voting Power
128,520.00 | | 7 | Sole Dispositive Power
0.00 | | 8 | Shared Dispositive Power
128,520.00 |
|
| 9 | Aggregate Amount Beneficially Owned by Each Reporting Person
128,520.00 |
| 10 | Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
 |
| 11 | Percent of class represented by amount in row (9)
0.1 % |
| 12 | Type of Reporting Person (See Instructions)
IN |
Comment for Type of Reporting Person: The amounts reported in rows 6, 8 and 9 represent shares held directly by Frazier Life Sciences X, L.P. and do not include any warrants held directly by Frazier Life Sciences X, L.P. See item 4(a) to this Schedule 13G/A.
The percentage listed in row 11 is calculated based on 103,436,416 shares of Common Stock outstanding on June 12, 2026, as set forth in the Issuer's Definitive Proxy Statement on Schedule 14A filed with the SEC on June 29, 2026.